Put an oven rack in the middle position. Heat the oven to 350° F. Line 6 cups of a muffin tin with paper cupcake liners. Alternatively, you can lightly grease the muffin tin if you don't have cupcake liners.
In a medium bowl, whisk together the flour, pumpkin spice, baking powder, baking soda, and salt. Set aside.
In a large bowl, mix together the melted butter, maple syrup, pumpkin puree, and vanilla.
Add the flour mixture into the pumpkin mixture, and stir together until just combined.
Scoop the batter evenly amongst the lined muffin tin. Put the muffins in the oven and bake for 25 minutes.
Take the muffins out of the oven, remove the muffins from the muffin tin, and let cool on a wire rack for 10 minutes. Enjoy!